6. Urinary Bladder Cancer

Urinary Bladder Cancer Treatment

Several drugs have shown in vitro and in vivo pharmacological activity against urinary bladder cancer. This review aims at compiling the different drugs evaluated in in vitro and in vivo models of urinary bladder cancer and to review the advantages and limitations of both types of models, as well as the different methodologies applied for evaluating antineoplastic drug activity. Cancer is one o...

Urinary Bladder Cancer

Bladder cancer occurs after the fifth decade and more frequently in men than in women (sex ratio 2:1 to 3:1). It has been associated mainly with smoking, but also with occupational exposure to carcinogens from aniline dyes, paints, rubber, etc, and chronic irritation of the bladder mucosa due to bladder stones, or schistosomiasis. The main symptom is painless hematuria, which in the adult patie...

Urinary markers for bladder cancer

Bladder cancer has the fifth highest incidence of all malignancies in the United States, with a propensity to recur, requiring lifelong surveillance after diagnosis. Urinary markers of disease have been of extreme interest in this field in an effort to simplify surveillance schedules and improve early detection of tumors. Many markers have been described, but most remain investigational. Howeve...

Urothelial Bladder Cancer Urinary Biomarkers

Urothelial bladder cancer is the fourth most prevalent male malignancy in the United States and also one of the ten most lethal. Superficial or non-muscle-invasive bladder cancer has a high rate of recurrence and can progress to muscle invasive disease. Conventional surveillance requires regular cystoscopy and is used often with urinary cytology. Unfortunately, the cystoscopy procedure is invas...

Causation of Urinary Bladder Cancer